Transient Tachypnea of the Newborn Is Associated With an Increased Risk of Hospitalization Due to Respiratory Syncytial Virus Bronchiolitis

by Santtu Heinonen, MD, PhD; Liina Süvari, MD; Mika Gissler; Olli Pitkänen, MD, PhD; Sture Andersson, MD, PhD; Otto Helve, MD, PhD

Published in The Pediatric Infectious Disease Journal, April 2019.doi: 10.1097/INF.0000000000002057

 

 

Transient tachypnea of the newborn (TTN) is a self-limiting respiratory disorder, resulting from a failure to clear the lungs of perinatal fluid. As similar pathophysiologic features are present in children with respiratory syncytial virus (RSV) bronchiolitis, researchers hypothesized that these two conditions may be connected.

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Bordetella pertussis Infection in Infants and Young Children in Shanghai, China, 2016–2017: Clinical Features, Genotype Variations of Antigenic Genes and Macrolides Resistance

by Pan Fu, MS; Chuanqing Wang, MD, PhD; He Tian, MS; Zhihua Kang, PhD; Mei Zeng, MD, PhD

Published inThe Pediatric Infectious Disease Journal, April 2019. doi: 10.1097/INF.0000000000002160

 

 

The global resurgence of pertussis in countries with high vaccination coverage has been a concern of public health.

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Characteristics and Outcomes of Young Children Hospitalized With Laboratory-confirmed Influenza or Respiratory Syncytial Virus in Ontario, Canada, 2009–2014

by Sarah A. Buchan, PhD; Hannah Chung, MPH; Timothy Karnauchow, PhD; J. Dayre McNally, MD, PhD; Michael A. Campitelli, MPH; Jonathan B. Gubbay, MD; Kevin Katz, MD; Allison J. McGeer,  MD; David C. Richardson, MD; Susan E. Richardson, MD; Andrew Simor, MD; Marek Smieja, MD, PhD; George Zahariadis, MD; Dat Tran, MD; Natasha S. Crowcroft, MD (Cantab); Laura C. Rosella, PhD, MHSc; Jeffrey C. Kwong, MD, MSc.

Published in The Pediatric Infectious Disease Journal, April 2019. doi: 10.1097/INF.0000000000002164

 

 

Respiratory illnesses are a major contributor to pediatric hospitalizations, with influenza and respiratory syncytial virus (RSV) causing substantial morbidity and cost each season. Researchers compared the characteristics and outcomes of children 0–59 months of age who were hospitalized with laboratory-confirmed influenza or RSV between 2009 and 2014 in Ontario, Canada.

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The Risk of Serious Bacterial Infection in Febrile Infants 0–90 Days of Life With a Respiratory Viral Infection

by Erin G. Nicholson, MD; Vasanthi Avadhanula, PhD; Laura Ferlic-Stark, MS; Kirtida Patel, BS; Karen E. Gincoo, BS; Pedro A. Piedra, MD

Published in The Pediatric Infectious Disease Journal, April 2019. doi: 10.1097/INF.0000000000002165

 

 

Molecular diagnostic methods enhance the sensitivity and broaden the spectrum of detectable respiratory viruses in febrile infants ≤90 days of life. Researchers describe the occurrence of respiratory viruses in this population, as well as the rates of serious bacterial infection (SBI) and respiratory viral coinfection with regard to viral characteristics.

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Culture-confirmed Tuberculosis in South African Infants Younger Than 3 Months of Age: Clinical Presentation and Management of Respiratory Complications

by Lisa Frigati, MMED; Adrie Bekker, PhD; Silvia Stroebele, MMED; Pierre Goussard, PhD; H. Simon Schaaf, PhD

Published in The Pediatric Infectious Disease Journal, April 2019. doi: 10.1097/INF.0000000000002163

 

 

Little is known about the course and management of perinatal tuberculosis (TB). This publication describes the presentation, medical and surgical management of culture-confirmed TB in infants younger than 3 months of age.

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