Bioaerosol Sampling to Detect Avian Influenza Virus in Hanoi’s Largest Live Poultry Market

by Vuong N Bui, Tham T Nguyen, Hung Nguyen-Viet, Anh N Bui, Katie A McCallion, Hu Suk Lee, Son T Than, Kristen K Coleman, and Gregory C Gray

Published in Clinical Infectious Diseases, 05 March 2019. https://doi.org/10.1093/cid/ciy583

 

 

Newly emergent and virulent strains of H7N9 avian influenza virus are rapidly spreading in China and threaten to invade Vietnam. Researchers sought to introduce aerosol sampling for avian influenza viruses in Vietnam.

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Procalcitonin to guide antibiotic decision making

by Angela Branche, Olivia Neeser, Beat Mueller, and Philipp Schuetz

Published in Current Opinion in Infectious Diseases, scheduled for release April 2019. doi: 10.1097/QCO.0000000000000522

 

 

There is convincing evidence linking antibiotic-stewardship efforts which include the infection marker procalcitonin (PCT) to more rational use of antibiotics with improvements in side-effects and clinical outcomes. This is particularly true in the setting of respiratory infection and sepsis. Yet, some recent trials have shown no benefit of PCT-guided care. Researchers aimed to discuss the benefits and limitations of using PCT for early infection recognition, severity assessment and therapeutic decisions in individual patients based on most the recent study data.

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Dual wireless epidermal electronic systems with in-sensor analytics for neonatal intensive care

by Ha Uk Chung, Bong Hoon Kim, Jong Yoon Lee, Jungyup Lee, Zhaoqian Xie, Erin M. Ibler, Kun Hyuck Lee, Anthony Banks, Ji Yoon Jeong, Jongwon Kim, Christopher Ogle, Dominic Grande, Yongjoon Yu, Hokyung Jang, Pourya Assem, Dennis Ryu, Jean Won Kwak, Myeong Namkoong, Jun Bin Park, Yechan Lee, Do HoonKim, Arin Ryu, Jaeseok Jeong, Kevin You, Bowen Ji, Zhuangjian Liu, Qingze Huo, Xue Feng, Yujun Deng, Yeshou Xu, Kyung-In Jang, Jeonghyun Kim, Yihui Zhang, Roozbeh Ghaffari, Casey M. Rand, Molly Schau, Aaron Hamvas, Debra E. Weese-Mayer, Yong gang Huang, Seung Min Lee, Chi Hwan Lee, Naresh R. Shanbhag, Amy S. Paller, Shuai Xu, and John A. Rogers

Published in Science, 01 March 2019. DOI: 10.1126/science.aau0780

 

 

Neonatal care, particularly for premature babies, is complicated by the infants' fragility and by the need for a large number of tethered sensors to be attached to their tiny bodies. Chung et al. developed a pair of sensors that only require water to adhere to the skin and allow for untethered monitoring of key vital signs (see the Perspective by Guinsburg). On-board data processing allowed for efficient wireless near-field communication using standard protocols. The absence of cables makes it easier to handle the infants and allows for skin-to-skin contact between the babies and their parents or caregivers.

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Contact-Based Methods for Measuring Respiratory Rate

by Carlo Massaroni, Andrea Nicolò, Daniela Lo Presti, Massimo Sacchetti, Sergio Silvestri and Emiliano Schena

Published in Sensors, 21 February 2019. https://doi.org/10.3390/s19040908

 

 

There is an ever-growing demand for measuring respiratory variables during a variety of applications, including monitoring in clinical and occupational settings, and during sporting activities and exercise. Special attention is devoted to the monitoring of respiratory rate because it is a vital sign, which responds to a variety of stressors. There are different methods for measuring respiratory rate, which can be classed as contact-based or contactless. The present paper provides an overview of the currently available contact-based methods for measuring respiratory rate. For these methods, the sensing element (or part of the instrument containing it) is attached to the subject’s body. Methods based upon the recording of respiratory airflow, sounds, air temperature, air humidity, air components, chest wall movements, and modulation of the cardiac activity are presented. Working principles, metrological characteristics, and applications in the respiratory monitoring field are presented to explore potential development and applicability for each method.  Article access can be found here.    
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A Clinical Prediction Rule to Identify Febrile Infants 60 Days and Younger at Low Risk for Serious Bacterial Infections

by Nathan Kuppermann, MD, MPH; Peter S. Dayan, MD, MSc; Deborah A. Levine, MD; et al

Published in JAMA Pediatrics, 18 February 2019. doi:10.1001/jamapediatrics.2018.5501

 

 

In young febrile infants, serious bacterial infections (SBIs), including urinary tract infections, bacteremia, and meningitis, may lead to dangerous complications. However, lumbar punctures and hospitalizations involve risks and costs. Clinical prediction rules using biomarkers beyond the white blood cell count (WBC) may accurately identify febrile infants at low risk for SBIs. The objective of this study was to derive and validate a prediction rule to identify febrile infants 60 days and younger at low risk for SBIs.

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